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. 2015 Jan 6;6(2):679–695. doi: 10.18632/oncotarget.2707

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Copyright: © 2015 Buzzelli et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Stomach immune infiltrate in gp130^757FF xIL-1RT1^−/− mice compared to gp130^757FF mice; (i) MDSCs, (ii) Neutrophils, (iii) Macrophages, (iv) CD4⁺ T cells and (v) CD8⁺ T cells. (B) Proximal stomach mRNA expression of immune modulating genes in gp130^757FF xIL-1RT1^−/− cohort mice; (i) IL-1α (ii) IL-1β (iii) MIP2 (iv) TNFα (v) IL-23 (vi) Amphiregulin (vii) Arg-1 (viii) S100A8 & (ix) S100A9. (C) (i–iii) Assessment of distal tumor size in gp130^757FF xTNFα^−/− mice compared to gp130^757FF mice. p-values are as indicated for statistically significant changes (p < 0.05).