Table 1.
The CD4+ and CD8+ cell counts in whole-blood samples obtained 12 and 36 h after mononuclear cell secretome treatment (n = 4–5)
| CD4+ (%) | CD8+ (%) | CD4/CD8 ratio | CD4+/7-AAD pos | |
|---|---|---|---|---|
| 12 h | ||||
| Medium | 19.9 ± 1.3 | 10.8 ± 1.9 | 2.1 ± 0.3 | 8.1 ± 0.7 |
| MNC secretome | 13.3 ± 1.0 | 9.3 ± 2.0 | 1.7 ± 0.4 | 8.8 ± 2.8 |
| 36 h | ||||
| Medium | 23.9 ± 1.6 | 7.4 ± 1.1 | 2.9 ± 0.2 | 5.4 ± 0.5 |
| MNC secretome | 19.1 ± 2.4 | 9.3 ± 0.5 | 2.0 ± 0.1 | 10.6 ± 1.1 |
The CD4+/CD8+ cell ratio was reduced in treated animals when compared with controls. Additionally, CD4+/7-AAD positive cells were found more frequently.