Table III.
Measures of association between first trimester urinary phthalate metabolite concentrations and genital measurements in newborn boys1,2 in multivariable models.
| Boys | AGDAS |
AGDAP |
PW |
||||||
|---|---|---|---|---|---|---|---|---|---|
| β | 95% CI | P-value | β | 95% CI | P-value | β | 95% CI | P-value | |
| MEHP | −1.12 | (−2.16, −0.07) | 0.036 | −1.21 | (−2.43, −0.01) | 0.051 | −0.26 | (−0.57, 0.06) | 0.107 |
| MEOHP | −1.43 | (−2.49, −0.38) | 0.008 | −1.60 | (−2.84, −0.36) | 0.011 | −0.26 | (−0.58, 0.06) | 0.113 |
| MEHHP | −1.28 | (−2.29, −0.27) | 0.013 | −1.47 | (−2.65, −0.29) | 0.015 | −0.24 | (−0.54, 0.09) | 0.128 |
| MECPP | −0.97 | (−2.12, 0.18) | 0.097 | −0.93 | (−2.27, 0.41) | 0.171 | −0.32 | (−0.66, 0.02) | 0.065 |
| ΣDEHP | −1.26 | (−2.40, −0.13) | 0.029 | −1.35 | (−2.67, −0.02) | 0.046 | −0.31 | (−0.64, 0.04) | 0.078 |
| MEP | −0.32 | (−1.04, 0.39) | 0.374 | −0.03 | (−0.87, 0.82) | 0.953 | −0.12 | (−0.33, 0.10) | 0.275 |
| MBzP | 0.16 | (−0.81, 1.12) | 0.750 | 0.38 | (−0.64, 1.50) | 0.507 | 0.001 | (−0.29, 0.29) | 0.994 |
| MBP | −0.91 | (−2.02, 0.20) | 0.108 | −0.78 | (−2.08, 0.51) | 0.235 | −0.03 | (−0.36, 0.31) | 0.877 |
| MiBP | −0.49 | (−1.69, 0.72) | 0.427 | −0.49 | (−1.89, 0.91) | 0.490 | −0.07 | (−0.43, 0.29) | 0.699 |
| MCPP | 0.18 | (−0.60, 0.95) | 0.654 | 0.35 | (−0.56, 1.26) | 0.447 | −0.10 | (−0.33, 0.12) | 0.413 |
| MCNP | 0.31 | (−0.71, 1.33) | 0.551 | 0.14 | (−1.06, 1.34) | 0.816 | 0.10 | (−0.21, 0.40) | 0.537 |
| MCOP | 0.39 | (−0.39, 1.16) | 0.326 | −0.02 | (−0.93, 0.88) | 0.958 | −0.05 | (−0.28, 0.18) | 0.681 |
1
Adjusted for age at exam, weight-for-length Z-score, gestational age at birth, center and time of day of urine collection and maternal age.
2
Phthalate metabolite concentrations <LOD set to LOD/(√2).