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Subclonal reconstruction algorithms applied to breast tumor PD4120. Left: Area under the precision–recall curve (AUPRC) for PhyloWGS, PyClone and SciClone when looking at SSMs in areas of normal copy number. Right: AUPRC for PhyloWGS, PyClone and SciClone when looking at SSMs in areas of altered and normal copy number. CN, copy number; SSM, simple somatic mutation.
