Table 1.
Effect on haematological and serum biochemical parameters in absence (NaAsO 2 ) and presence of AEIA (AEIA + NaAsO 2 ) in mouse
| Groups | Parameters | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Total erythrocyte count (x10 6/ mm 3 ) | Haemoglobin (g/dl) | ALT (IU/l) | AST (IU/l) | Urea (mg/dl) | Lactate dehydrogenase (U/l) | Creatinine kinase (IU/ mg protein) | Cholesterol (mg/dl) | Triglycerides (mg/dl) | |
| I | 6.05 ± 0.28 | 9.12 ± 0.79 | 72.21 ± 4.11 | 53.33 ± 3.44 | 24.17 ± 2.25 | 32.48 ± 2.11 | 205.56 ± 12.33 | 132.45 ± 7.11 | 122.41 ± 7.12 |
| II | 3.25 ± 0.22# | 5.24 ± 0.76# | 154.22 ± 7.43# | 78.35 ± 4.72# | 58.11 ± 3.41# | 64.04 ± 3.50# | 284.67 ± 16.17$ | 191.14 ± 7.22# | 238.33 ± 10.94# |
| III | 4.98 ± 0.27** | 8.17 ± 0.54** | 105.23 ± 5.02* | 59.67 ± 3.92** | 42.14 ± 2.01** | 54.92 ± 3.88* | 231.71 ± 17.92* | 161.45 ± 6.25* | 168.85 ± 9.15** |
Values were expressed as mean ± SE (n = 6). #Values differ significantly from normal control (p < 0.01). $Values differ significantly from normal control (p < 0.01). *Values differ significantly from NaAsO2 control (p < 0.05). **Values differ significantly from NaAsO2 control (p < 0.01). Group I: Normal control; Group II: NaAsO2 (10 μM) control; Group III: NaAsO2 (10 μM) + AEIA (400 μg/ml).