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. 2014 Dec 11;2:168. doi: 10.1186/s40478-014-0168-9

Figure 7.

Figure 7

FGF1 decelerates differentiation of monocultured oligodendrocytes. (a) FGF1 does not affect proliferation of primary murine OPCs but (b) decelerates the differentiation into myelinating oligodendrocytes as determined by morphology; Two-way ANOVA with Bonferroni post correction **p < 0.01; *p < 0.05. The expression of myelin-associated genes was assessed by qPCR on samples from OPCs (6 h), immature (24 h) and mature cells (48 h). The expression levels of (c) Mbp, (d) Mag and in (e) Mog are reduced due to increasing FGF1 concentrations; one-way ANOVA with Bonferroni post correction *** p < 0.001 **P < 0.01; *P = <0.05; error bars represent SEM from three independent experiments.