Table 2.
Variant mtLSU and dihydropteroate synthetase ( DHPS ) genotypes in patients with P. jirovecii pneumonia
| Genotype (n = 95) | mtLSU | DHPS | ||
|---|---|---|---|---|
| Nucleotide position/identity | No. (%) | Nucleotide position/identity | No. (%) | |
| 1 | 85C/248C | 41 (43.2) | 165 (55)/A (Thr); 171 (57)/C (Pro) | 95 (100) |
| 2 | 85A/248C | 5 (5.2) | 165 (55)/G (Ala); 171 (57)/C (Pro) | 0 (0.0) |
| 3 | 85T/248C | 21 (22.1) | 165 (55)/A (Thr); 171 (57)/T (Ser) | 0 (0.0) |
| 4 | 85C/248T | 1 (1.0) | 165 (55)/G (Ala); 171 (57)/T (Ser) | 0 (0.0) |
| Mixed (total) | 27 (28.1) | |||
| 1 and 2 | 13 (13.5) | |||
| 1 and 3 | 11 (11.5) | |||
| 2 and 3 | 3 (3.1) | |||