Table 5.

Comparison of the diagnostic performance of serum fibulin-4, CA-125, CA19-9, fibulin-4 + CA-125, fibulin-4 + CA19-9, CA-125 + CA19-9 and fibulin-4 + CA-125 + CA19-9

Marker	Sensitivity (%)	Specificity (%)	Positive predictive value (%)	Negative predictive value (%)	Positive likelihood ratio	Negative likelihood ratio
fibulin-4	75.0	84.0	88.2	67.7	4.69	0.30
CA-125	70.6	79.0	84.3	62.7	3.36	0.37
CA19-9	61.3	70.0	76.6	53.0	2.04	0.55
fibulin-4 + CA-125	68.8	92.0	93.2	64.8	8.59	0.34
fibulin-4 + CA19-9	60.6	90.0	90.6	58.8	6.06	0.44
CA-125 + CA19-9	56.3	88.0	88.2	55.7	4.69	0.50
fibulin-4 + CA-125 + CA19-9	52.5	98.0	97.7	56.3	26.25	0.48