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. 2015 Mar 8;16:83. doi: 10.1186/s13063-015-0594-4

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© Casper et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Study flowchart. Overall, 186 patients meeting the inclusion criteria and no exclusion criteria are randomly assigned to two treatment arms. Especially, present SBP has to be ruled out, and patients have to be verified to carry at least one of the three common NOD2 variants. It is expected that about 1,400 patients need to be evaluated to finally randomize the calculated 186 patients. SBP, Spontaneous bacterial peritonitis.