Table 5.
Morgan-Russell subscale C (mental state); dose–response analysis
| Dose | AN study 2 | AN study 3 | AN study 4 | Analysis for time trend doubly ordered r × c contingency tables Linear-by-linear association test | Exact Monte Carlo | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Response category | Response category | Response category | Test Statistic | P (99% CI) | ||||||||||
| 0 | 4 | 8 | 12 | 0 | 4 | 8 | 12 | 0 | 4 | 8 | 12 | |||
| Never ASD | 0 | 4 | 12 | 18 | 0 | 5 | 9 | 20 | 0 | 6 | 8 | 20 | 0 | 1 (0.9995 to 1) |
| ASD × 1-3 | 0 | 3 | 1 | 6 | 0 | 1 | 4 | 5 | 0 | 2 | 3 | 5 | 0 | 1 (0.9995 to 1) |
| ASD × 4 | 1 | 3 | 0 | 2 | 1 | 3 | 1 | 1 | 2 | 1 | 3 | 0 | −0.561 | 0.69 (0.67 to 0.7) |
| Dose–response analysis | ||||||||||||||
| Doubly ordered r × c contingency tables | Linear-by-linear association test | Linear-by-linear association test | Linear-by-linear association test | Stratified r × c contingency tables Cochran-Mantel-Haenszel test | ||||||||||
| Test statistic | −1.452 | −2.56 | −2.787 | −4.342 | ||||||||||
| Exact Monte Carlo P | 0.15 | 0.008 | 0.007 | 0.0001 | ||||||||||
| 99% CI | 0.14 to 0.16 | 0.005 to 0.01 | 0.005 to 0.009 | 0 to 0.0004 | ||||||||||
AN anorexia nervosa, AN study 2 second anorexia nervosa examination, AN study 3 third anorexia nervosa examination, AN study 4 fourth anorexia nervosa examination, ASD autism spectrum disorders, never ASD individuals who had never been assigned an ASD diagnosis, ASD × 1–3 those who had been assigned an ASD diagnosis in at least one study, but not at all four studies, ASD × 4 those with an ASD diagnosis at all four examinations, CI confidence interval, r × c rows and columns.