Table 3.
Meta-regression analyses
| Factor | Ratio of odds ratio (95% CI) | P-value | Explained variance (%) |
|---|---|---|---|
| Country’s income group | 0.0 | ||
| High-income | 1.10 (0.75 to 1.61) | 0.632 | |
| Middle-income | 0.83 (0.49 to 1.40) | 0.489 | |
| Low-income | 1 (reference) | ||
| Publication year | 17.4 | ||
| 1993 to 2000 | 1 (reference) | ||
| 2001 to 2005 | 1.97 (1.33 to 2.92) | 0.001 | |
| 2006 to 2010 | 1.97 (1.33 to 2.92) | 0.001 | |
| 2011 to 2013 | 2.07 (1.26 to 3.39) | 0.004 | |
| Study design | 1.0 | ||
| Cross-sectional | 0.87 (0.70 to 1.08) | 0.208 | |
| Cohort | 1 (reference) | ||
| Sample size | 23.3 | ||
| Less than 100 | 1 (reference) | ||
| 100 to 500 | 1.48 (1.15 to 1.91) | 0.002 | |
| 500 or more | 1.85 (1.39 to 2.47) | 0.000 | |
| Depression rate | 30.1 | ||
| Less than 20% | 1 (reference) | ||
| 20 to 50 % | 0.96 (0.68 to 1.35) | 0.815 | |
| 50% plus | 0.68 (0.47 to 0.99) | 0.044 | |
| Adherence rate | 5.0 | ||
| Less than 50% | 1 (reference) | ||
| 50 to 75% | 1.34 (0.94 to 1.94) | 0.102 | |
| 75% plus | 1.28 (0.89 to 1.84) | 0.182 | |
| Adherence measure | 0.0 | ||
| Self-reported | 1 (reference) | ||
| Pharmacy refills | 1.09 (0.77 to 1.54) | 0.628 | |
| Pill count | 0.98 (0.57 to 1.68) | 0.948 | |
| MEMS cap | 0.82 (0.56 to 1.20) | 0.299 |