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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2014 Dec 31;21(4):738–745. doi: 10.1016/j.bbmt.2014.12.028

Table 5. Multivariate Analyses of Risk Factors for the development of Second Primary Malignancies among Autotransplant Recipients who developed a new cancer.

Overall for Risk of developing any new cancer (n=4,129)
Parameter Hazard Ratio (95% CI) P-value
 Female vs. male 0.50 (0.35-0.71) 0.0001
Age group Overall test P-value <0.0001
 40-49 vs. 18-39 1.62 (0.36-7.13) 0.5240
 50-59 vs. 18-39 3.03 (0.73-12.46) 0.1240
 60-69 vs. 18-39 6.07 (1.48-24.78) 0.0120
 70+ vs. 18-39 8.58 (1.95-37.74) 0.0045
Body Mass Index (BMI) Overall test P-value =0.0048
 Overweight vs. (underweight + normal) 1.27 (0.81-1.98) 0.2866
 Obesity 1.93 (1.25-2.99) 0.0030
Risk of AML/MDS (n=3,977)
Parameter Hazard Ratio (95% CI) P-value
Age group Overall test P-value = 0.0141
 50-59 vs. 40-49 3.76 (0.86-16.46) 0.0785
 60-69 vs. 40-49 3.95 (0.88-17.70) 0.0730
 70+ vs. 40-49 13.17 (2.52-68.86) 0.0022