Table 5. Multivariate Analyses of Risk Factors for the development of Second Primary Malignancies among Autotransplant Recipients who developed a new cancer.
Overall for Risk of developing any new cancer (n=4,129) | ||
---|---|---|
Parameter | Hazard Ratio (95% CI) | P-value |
Female vs. male | 0.50 (0.35-0.71) | 0.0001 |
Age group | Overall test P-value <0.0001 | |
40-49 vs. 18-39 | 1.62 (0.36-7.13) | 0.5240 |
50-59 vs. 18-39 | 3.03 (0.73-12.46) | 0.1240 |
60-69 vs. 18-39 | 6.07 (1.48-24.78) | 0.0120 |
70+ vs. 18-39 | 8.58 (1.95-37.74) | 0.0045 |
Body Mass Index (BMI) | Overall test P-value =0.0048 | |
Overweight vs. (underweight + normal) | 1.27 (0.81-1.98) | 0.2866 |
Obesity | 1.93 (1.25-2.99) | 0.0030 |
Risk of AML/MDS (n=3,977) | ||
Parameter | Hazard Ratio (95% CI) | P-value |
Age group | Overall test P-value = 0.0141 | |
50-59 vs. 40-49 | 3.76 (0.86-16.46) | 0.0785 |
60-69 vs. 40-49 | 3.95 (0.88-17.70) | 0.0730 |
70+ vs. 40-49 | 13.17 (2.52-68.86) | 0.0022 |