Table 1.
Predictions | Evidence | ||||
---|---|---|---|---|---|
| |||||
SLI | Dyslexia | Autism Spectrum Disorder | Tourette syndrome | OCD | |
Increased reliance (from either spontaneous learning or therapy) on strategies thought to depend on declarative memory |
|
|
|
Habit reversal therapy, which involves the explicit control of tics, is effective in TS (Frank and Cavanna, 2013; Himle et al., 2006) | Habit reversal therapy, as well as other cognitive behavioral therapies, are effective in OCD (March, 1995; Watson and Rees, 2008) |
| |||||
Increased reliance on the neural system underlying declarative memory | Electrophysiological evidence: N400 ERP components found for grammatical processing (Fonteneau and van der Lely, 2008; Neville et al., 1993; Ullman and Pierpont, 2005) |
|
fMRI evidence: Increased activation in medial temporal lobe structures during some social processing tasks (Dichter et al., 2012; Vaidya et al., 2011) | TBD | fMRI and PET evidence: Increased activation in MTL structures (and decreased activation in the basal ganglia) during procedural memory and executive tasks (Rauch et al., 1997; Rauch et al., 2007; Rauch et al., 2001; Roth et al., 2003; van den Heuvel et al., 2005) |
| |||||
Indicators of better declarative memory are associated with better compensation | Better grammatical abilities in individuals with better declarative memory (Lum et al., 2012) | Better reading ability in individuals with better declarative memory and larger hippocampi/MTL structures (Hedenius et al., 2013; Krafnick et al., 2011) | TBD |
|
OCD symptoms better in individuals with larger hippocampi/MTL structures (Carmona et al., 2007; Peterson et al., 2007; van den Heuvel et al., 2009) |
Note. SLI: specific language impairment. TS: Tourette syndrome. OCD: obsessive-compulsive disorder. TBD: To be determined; we are not aware of any relevant studies. (f)MRI: (functional) magnetic resonance imaging. PET: positron emission tomography. ERP: event-related potential. MTL: medial temporal lobe.