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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: J Neurochem. 2015 Jan 29;132(6):622–628. doi: 10.1111/jnc.13023

Figure 2.

Figure 2

Effects of lipocalin-2 (LCN2) on intracellular levels of labile iron and ROS generation in rat brain endothelial cells. Treatment with 1µg/ml of LCN2 for 3hrs significantly reduced fluorescent intensity of calcein-AM (a) and increased fluorescent intensity of CM-H2DCFDA (b) in RBE.4 cells. *, p<0.05 compared with the control group. (c) Western blot showed that RBE.4 cells expressed the two major receptors of LCN2, including LRP2 and 24p3R.