Table 4.
N1/N2 | Odds Ratio | p-value | |
---|---|---|---|
Banking practice | |||
Group 1 | 96/116 | 1.00 | |
Group 2 | 218/270 | 0.94 (0.51 – 1.73) | 0.85 |
Group 3 | 106/132 | 0.93 (0.47 – 1.84) | 0.84 |
Gender | |||
Female | 199/260 | 1.00 | |
Male | 221/258 | 1.84 (1.16 – 2.91) | 0.01 |
Disease status | |||
Early | 165/193 | 1.00 | |
Intermediate | 183/222 | 0.82 (0.48 – 1.40) | 0.47 |
Advanced | 72/103 | 0.44 (0.24 – 0.80) | 0.007 |
Unit processing at transplant center | |||
No wash / DMSO dilution | 84/108 | 1.00 | |
Thaw/wash + dextran reconstitution | 314/376 | 1.82 (1.02 – 3.23) | 0.04 |
Transplant period | |||
2000–2004 | 61/83 | ||
2005 – 2011 | 359/435 | 2.06 (1.14 – 3.72) | 0.02 |
Odds ratios >1 indicate better outcome
N1 = number alive; N2 = number evaluable
Group 1 : automated processing, units were plasma and red blood cell reduced or buffy coat production method
Group 2 : manual processing, units were plasma and red blood cell reduced or buffy coat production method
Group 3 : manual processing, units were plasma reduced
Early risk = patients in first complete remission / refractory anemia
Intermediate risk = patients in second complete remission
Advanced = patients in relapse / refractory anemia with excess blasts