Table 3.

Brain Region	[3H]DAMGO MOR Relative Binding
	Titi Monkey	Human1,2,3	Macaque4	Rat5,6	Prairie Vole7,8	Montane Vole7	Guinea Pig6
Cingulate Gyrus	+			+++	++	+
Striatum
Caudate	+	++	+	++++	++++	++	++++
Putamen	+	++	+	++++	++++	++	++++
Nucleus Accumbens Shell	++	+	+	++++	+++	++	+++
Nucleus Accumbens Core	++	++	+	++++	+++	++	+++
NUDAP	+++	++++	+++	N/A	N/A	N/A	N/A
Claustrum	0	+		0	0	0	0
Globus Pallidus Internal	0	+		+	+	+
Ventral Pallidum	0
Amygdala/Extended Amygdala		+++
Anterior Amygdala	+++		++
Basolateral Amygdala	++		+++	++++			++
Basomedial Amygdala	++		+++
Cortical Amygdala	++		+++	++++			++
Medial Amygdala	++++		++++	+++	++	++	++
Central Amygdala	0		+	+			+
Paralaminar n.	+++		++++
Lateral Amygdala	+		++	++++			++
Bed Nucleus of the Stria
Terminalis	++		++	++	+	+	++
Septal Region
Medial Septum	++			+++
Lateral Septum	++			0	++	+
Diagonal Band	++			++
Hippocampus
Septohippocampal n.	+++			++			+
Presubiculum	+			++++
Entorhinal cortex	+			+
CA1	0				0	+
CA3	0			+++
Hypothalamus
Anterior hypothalamic n.	+++			0	+	+
Arcuate N.	++			0
Dorsomedial hypothalamic n.	++			+	+
Lateral hypothalamic n.	++			+	+	+
Medial preoptic area	+++			+
Paraventricular hypothalamic n.	++++			0
Suprachiasmatic hypothalamic n.	+++
Supraoptic hypothalamic. N.	+++			0
Ventromedial hypothalamic n.	++			0	++	+
Septohypothalamic n.	++
Mammillary body	++			+++	++	+
Substantia Nigra	+			+++	+	+
Thalamus
Anteroventral thalamic n.	++				+++	+
Ventrolateral thalamic n.	++			0
ventral anterior thalamic n.	+
Mediodorsal thalamic n.	++	+++		++++	+	+
Pulvinar	++
Interpeduncular n.	++++			++++	++++	++++

¹Voorn et al., 1996

²Pilapil et al., 1987

³Berthele et al., 2005

⁴Daunais et al., 2001

⁵Mansour et al., 1987

⁶Sharif and Hughes, 1989

⁷Inoue et al., 2013

⁸Resendez et al., 2012

++++, very dense

+++ dense

++ moderate

+ light, 0 not detectable, N/A not applicable, blank cells = no data