Table 5.
Parameter and age at prophylaxis start, years | Current age, years |
|||
---|---|---|---|---|
12−16 | 17−21 | 22−26 | 27−35 | |
All joint bleeds | ||||
<2 (primary), n | 4 | 8 | 9 | 4 |
Median (range) | 0.30 (0.0−1.4) | 0.10 (0.0−0.6) | 0.40 (0.0−1.4) | 0.20 (0.0−0.4) |
2 to <6 (secondary), n | 4 | 7 | 5 | 6 |
Median (range) | 4.10 (0.2−8.4) | 0.60 (0.0−14.6) | 0.20 (0.0−0.4) | 0.20 (0.0−4.0) |
6 to <12 (secondary), n | − | 12 | 12 | 3 |
Median (range) | − | 0.60 (0.0−4.0) | 0.80 (0.0−7.8) | 1.60 (0.4−2.0) |
12 to 18 (secondary), n | − | − | 7 | 14 |
Median (range) | − | − | 1.00 (0.2−4.6) | 0.90 (0.0−9.2) |
Never (on demand), n | − | 1 | 10 | 12 |
Median (range) | − | 10.4 (10.4−10.4) | 14.3 (10.8−54.6) | 13.9 (5.2−37.8) |
Index joint bleeds | ||||
<2 (primary), n | 4 | 8 | 9 | 4 |
Median (range) | 0.10 (0.0−1.2) | 0.00 (0.0−0.6) | 0.20 (0.0−0.8) | 0.10 (0.0−0.2) |
2 to <6 (secondary), n | 4 | 7 | 5 | 6 |
Median (range) | 2.50 (0.0−4.6) | 0.40 (0.0−10.6) | 0.20 (0.0−0.2) | 1.00 (0.0−2.0) |
6 to <12 (secondary), n | − | 12 | 12 | 3 |
Median (range) | − | 0.50 (0.0−3.6) | 0.50 (0.0−4.0) | 1.20 (0.4−1.6) |
12 to 18 (secondary), n | − | − | 7 | 14 |
Median (range) | − | − | 0.80 (0.2−3.8) | 0.50 (0.0−8.6) |
Never (on demand), n | − | 1 | 10 | 12 |
Median (range) | − | 6.2 (6.2−6.2) | 10.7 (5.8−39.4) | 9.10 (5.2−28.4) |