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. 2014 Dec 2;21(2):171–179. doi: 10.1111/hae.12539

Table 5.

Annualized number of joint bleeds in the previous 5 years

Parameter and age at prophylaxis start, years Current age, years
12−16 17−21 22−26 27−35
All joint bleeds
 <2 (primary), n 4 8 9 4
  Median (range) 0.30 (0.0−1.4) 0.10 (0.0−0.6) 0.40 (0.0−1.4) 0.20 (0.0−0.4)
 2 to <6 (secondary), n 4 7 5 6
  Median (range) 4.10 (0.2−8.4) 0.60 (0.0−14.6) 0.20 (0.0−0.4) 0.20 (0.0−4.0)
 6 to <12 (secondary), n 12 12 3
  Median (range) 0.60 (0.0−4.0) 0.80 (0.0−7.8) 1.60 (0.4−2.0)
 12 to 18 (secondary), n 7 14
  Median (range) 1.00 (0.2−4.6) 0.90 (0.0−9.2)
 Never (on demand), n 1 10 12
  Median (range) 10.4 (10.4−10.4) 14.3 (10.8−54.6) 13.9 (5.2−37.8)
Index joint bleeds
 <2 (primary), n 4 8 9 4
  Median (range) 0.10 (0.0−1.2) 0.00 (0.0−0.6) 0.20 (0.0−0.8) 0.10 (0.0−0.2)
 2 to <6 (secondary), n 4 7 5 6
  Median (range) 2.50 (0.0−4.6) 0.40 (0.0−10.6) 0.20 (0.0−0.2) 1.00 (0.0−2.0)
 6 to <12 (secondary), n 12 12 3
  Median (range) 0.50 (0.0−3.6) 0.50 (0.0−4.0) 1.20 (0.4−1.6)
 12 to 18 (secondary), n 7 14
  Median (range) 0.80 (0.2−3.8) 0.50 (0.0−8.6)
 Never (on demand), n 1 10 12
  Median (range) 6.2 (6.2−6.2) 10.7 (5.8−39.4) 9.10 (5.2−28.4)