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. 2015 Mar 1;2015:708282. doi: 10.1155/2015/708282

Table 2.

Nitration sites in plasma proteins identified by mass spectrometry.

Protein Nitrated Tyr Effect References
ApoA-11 Y166 and Y192 Decreased activation of LCAT and ABCA1 [59, 7779]
ApoB-1002 Y276, Y583, Y666, Y720, Y2524, Y3139, Y3295, Y3489, Y4141 Increased affinity for LOX-1, CD36, SR-A [69]
Fibrinogen β chain1 Y292, Y422 Accelerated clot formation [55]
Ig gamma-1 chain C region1 Y161, Y290 Unknown [18]
Ig kappa chain C region1 Y32, Y84 Unknown [18]
Ig lambda chain C region1 Y84 Unknown [18]
Ig mu chain C region1 Y276 Unknown [18]
Ig heavy chain V-III1 Y33, Y80, Y95 Unknown [18]
Zinc finger and BTB domain-containing protein 11 Y83 Unknown [18]
Protein EFR3 homolog B1 Y669 Unknown [18]

1Data from proteins immunocaptured from individuals diagnosed with CVD.

2Data from an electronegative LDL fraction isolated from plasma from healthy humans.