Table 2. Effect of chronic iodoacetamide pretreatment on gastric MPO activity and body weight gain of wild-type mice.
Test parameter | Control | Iodoacetamide |
---|---|---|
MPO activity (neutrophil equivalents/mg) | 3,134 ± 644 (7) | 9,997 ± 1,701 (7)* |
Body weight gain (g) | 0.83 ± 0.10 (6) | 0.61 ± 0.17 (6) |
Iodoacetamide (0.1 %) was added to the drinking water for 7 days, while control mice drank normal water. MPO activity in the gastric corpus wall was determined on the 8th day of pretreatment and expressed as neutrophil equivalents per mg tissue. The body weight gain was calculated as the difference in body weight before and after the 7 day pretreatment period. The values represent means ± SEM, n as indicated in brackets.
P < 0.01 versus control (Student’s t test).