Table 1.
The values of biochemical markers of experimental groups after 4 weeks of treatment with vehicle or resveratrol
|
FBS
(mg/dl) |
MDA
(nmol/ml) |
SOD
(Unit/ml) |
GR
(Unit/L) |
|
|---|---|---|---|---|
| DMC-V | 104.9±2.4 | 0.63±0.07 | 264.2±39.2 | 70.6±4.1 |
| DM-V | 209.0±4.4* | 1.55±0.11* | 92.9±11.3* | 26.4±2.8* |
| Sham-V | 106.1±2.6 | 0.64±0.07 | 243.5±43.9 | 68.8±3.9 |
| HTN-V | 120.4±1.5 | 1.32±0.13* | 147.4±19.7* | 39.4±3.1* |
| DM+HTN-V | 199.4±5.8* | 1.81±0.45* | 116.1±13.8* | 30.1±2.4* |
| DM+HTN-R5 | 123.6±2.7Δ | 0.63±0.08Δ | 265.6±51.1Δ | 62.8±5.1Δ |
| DM+HTN-R10 | 106.1±4.2Δ | 0.64±0.09Δ | 302.3±62.1Δ | 64.7±5.1Δ |
| DM+HTN-R20 | 102.6±5.4Δ | 0.56±0.07Δ | 276.1±61.5Δ | 65.4±3.7Δ |
DMC-V: Diabetic control group receiving vehicle; Sham-V: Sham-operated receiving vehicle; DM-V: Diabetic receiving vehicle; HTN-V: Hypertensive receiving vehicle; DM+HTN-V: Diabetic hypertensive receiving vehicle; DM+HTN-R5: Diabetic hypertensive receiving 5 mg/kg/day resveratrol; DM+HTN-R10: Diabetic hypertensive receiving 10 mg/kg/day resveratrol; DM+HTN-R20: Diabetic hypertensive receiving 20 mg/kg/day resveratrol; FBS: Fasting blood glucose; MDA: Malondialdehyde; SOD: Superoxide dismutase; GR: Glutathione reductase; Data are mean±SEM and n=8-10 in each group; *Significant difference (P<0.05) with DMC-Veh or Sham-V; ∆Significant difference (P<0.05) with DM+HTN-V