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Posterior 3D volume rendering of fused PET/CT scans of mice bearing breast tumors in the upper right flank and treated with fulvestrant. Upper panel: 18F-FES PET representative images. 18F-FES uptake decreases in xenografts with increased dose of fulvestrant. The gallbladder and bowel show high uptake consistent with hepatobiliary excretion of 18F-FES. Lower panel: 18F-FDG PET representative images. There is no difference among groups in 18F-FDG uptake. Green arrows indicate tumor.
