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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Clin Cancer Res. 2015 Jan 8;21(6):1395–1405. doi: 10.1158/1078-0432.CCR-14-2300

Figure 4. Combination cytotoxicity of RG7112 with vincristine, dexamethasone or L-asparaginase.

Figure 4

Dose response curves of the RS4;11 cell line and infant MLL-ALL xenografts to RG7112 (closed circles), vincristine, dexamethasone, or L-asparaginase (open triangles) and the relevant combinations (gray triangles). The concentrations used were 0.25, 0.5 1, 2, 4 × the IC50 values for each drug/cell type. Results shown are the mean ± SEM of 3 biological repeats.