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. 2014 Dec 31;113(6):1697–1711. doi: 10.1152/jn.00752.2014

Fig. 4.

Fig. 4.

D1 receptor (D1R) agonist SKF38393 facilitates dorsal striatum-evoked striatonigral IPSCs more strongly in DA-deficient Pitx3Null mice than in DA-intact Pitx3WT mice. A and B: averaged traces shown before, during and after bath application of 3 μM SKF38393 in Pitx3WT mice and Pitx3Null mice, respectively. C: pooled data showing 3 μM SKF38393 had a stronger facilitatory effect on striatonigral IPSCs in Pitx3Null mice than in Pitx3WT mice. *P < 0.05, unpaired t-test. D: pooled data showing 3 μM SKF38393 decreased paired pulse ratio [PPR; ratio of the second peak current over the first one (P2/P1)] in Pitx3WT and Pitx3Null mice. **P < 0.01, paired t-test. For the PPR during baseline and SKF38393 in Pitx3WT and Pitx3Null mice, P > 0.05, unpaired t-test.