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. 2014 Dec 31;113(6):1697–1711. doi: 10.1152/jn.00752.2014

Fig. 5.

Fig. 5.

D1R agonist SKF81297 facilitates dorsal striatum-evoked striatonigral IPSCs more strongly in DA-deficient Pitx3Null mice than in DA-intact Pitx3 WT mice. A and B: averaged traces shown before, during and after bath application of 1 μM SKF81297 in Pitx3WT mice and Pitx3Null mice, respectively. C: pooled data showing 1 μM SKF81297 had a stronger facilitatory effect on striatonigral IPSCs in Pitx3Null mice than in WT mice. **P < 0.01, unpaired t-test. D: pooled data showing 1 μM SKF81297 decreased PPR in Pitx3WT and Pitx3Null mice. *P < 0.05, paired t-test. For the PPR during baseline and SKF81297 in Pitx3WT and Pitx3Null mice, P > 0.05, unpaired t-test.