Table 5.
Comparison of active and passive properties of type II DG granule cells under different experimental conditions
| Wild-type (n = 8) | Tg2576 (n = 13) | Tg2576 + RSG (n = 11) | P | |
|---|---|---|---|---|
| First peak latency, ms | 265.3 ± 17.4 | 303.2 ± 26.8 | 296.5 ± 36 | 0.7 |
| Itrh, pA | 41.3 ± 5.5 | 36.9 ± 4.3 | 41.8 ± 2.9 | 0.6 |
| Vtrh, mV | −45.2 ± 2.7 | −43.9 ± 1.9 | −43 ± 1.9 | 0.8 |
| MRP, mV | −69.2 ± 0.9 | −72.9 ± 1.5 | −67.1 ± 2.3 | 0.06 |
| Rin, MΩ | 297.2 ± 13.6 | 345.7 ± 14.9 | 342.2 ± 22.4 | 0.16 |
| τ, ms | 31.9 ± 1.8 | 31.5 ± 2 | 30.7 ± 1.9 | 0.9 |
| Cm, pF | 108.7 ± 9 | 89.1 ± 7.1 | 88.5 ± 6.3 | 0.16 |
Tg2576 and RSG-treated Tg2576 were compared with wild-type. Data are mean ± SE. P values were obtained with 1-way ANOVA and post hoc Dunnett test.