Adipose inflammation and gene expression on HFD. Epididymal white adipose tissue (WAT) was collected from mice on HFD for 18 wk, and mRNA expression was analyzed in qRT-PCR. A: macrophage markers. B: proinflammatory genes. C: serum cytokines. D: lipogenic genes. E: adipocyte genes. All bar graphs represent means ± SE (n = 6). *P < 0.05 by Student's t-test. F4/80, F4/80 antigen, a glycoprotein expressed by macrophages; CD11b, integrin αM; CD11c, integrin αX; SREBP, sterol regulatory element-binding protein; FAS, fatty acid synthase; HSL, hormone-sensitive lipase; LPL, lipoprotein lipase; ACDC, adiponectin.