Fig. 7.
Effects of ERβ agonist [2,3-bis(4-hydroxyphenyl)-propionitrile, DPN] on food intake and Pi excretion. OVX rats were housed in metabolic cages and after 3 days of adjustment (baseline), they were injected daily with DPN (150 or 500 μg/100 g body wt) or vehicle for 3 days. A: time course of food intake before and after 150 μg/100 g body wt DPN injection. B: average of 3 days of food intake before (baseline, dark bars) or food consumed on the third day after vehicle or DPN injection (gray bars). C: average of 3 days Pi excretion/creatinine excretion before (baseline, dark bars) and Pi excretion/creatinine excretion of the third day after vehicle or DPN injection (gray bars). n = 4 rats in each group. *P < 0.001 vs. baseline of DPN group.