Table 1.
Sham | ACF | Sham + MitoQ | ACF + MitoQ | |
---|---|---|---|---|
Body weight, g | 475 ± 16 | 517 ± 11 | 470 ± 29 | 489 ± 17 |
Heart weight, g | 1.15 ± 0.04 | 2.11 ± 0.06* | 1.20 ± 0.04 | 2.33 ± 0.14* |
LV weight, g | 0.80 ± 0.02 | 1.37 ± 0.03* | 0.81 ± 0.04 | 1.37 ± 0.09* |
Right ventricular weight, g | 0.23 ± 0.01 | 0.46 ± 0.03* | 0.22 ± 0.01 | 0.43 ± 0.04* |
Lung weight, g | 1.6 ± 0.06 | 2.2 ± 0.06* | 1.6 ± 0.09 | 2.2 ± 0.17* |
Tibia length, mm | 49 ± 0.6 | 50 ± 0.3 | 49 ± 0.4 | 50 ± 0.5 |
Heart weight/body weight, g/g × 100 | 0.24 ± 0.007 | 0.409 ± 0.009* | 0.247 ± 0.007 | 0.426 ± 0.02* |
Number of rats/group | 7 | 7 | 8 | 8 |
Values are means ± SE. Animals were divided into the following groups: sham operation (sham), volume overload of aortocaval fistula (ACF), sham with mitoubiquinone (MitoQ) treatment (sham + MitoQ), and ACF with MitoQ treatment (ACF + MitoQ).
LV, left ventricular.
P < 0.05 vs. the sham group.