Fig. 1.
Passive limb movement (PLM)-induced hyperemia in young and old with and without intra-arterial NG-monomethyl-l-arginine (l-NMMA) infusion. A: absolute leg blood flow (LBF; ml/min). B: change in LBF, normalized for the resting reduction in LBF due to l-NMMA. C: LBF area under the curve (AUC) calculated as the summed second-by-second response during the first 60 s of movement. Values are means ± SE. To increase clarity of the data presented, only the first 60 s of PLM are displayed. One minute of baseline data was collected before PLM occurred. *P < 0.05, significant difference between control and l-NMMA.