Table 2.
Baseline hemodynamics with and without l-NMMA
| Young |
Old |
|||
|---|---|---|---|---|
| Control | l-NMMA | Control | l-NMMA | |
| Leg blood flow, ml/min | 310 ± 27 | 161 ± 16† | 217 ± 62 | 121 ± 50† |
| Leg vascular conductance, ml·min−1·mmHg−1 | 3.3 ± 0.3 | 1.7 ± 0.1† | 2.3 ± 0.6 | 1.3 ± 0.5† |
| Heart rate, beats/min | 54 ± 2 | 50 ± 2† | 59 ± 4 | 61 ± 6 |
| Stroke volume, ml/beat | 98 ± 6 | 96 ± 8 | 93 ± 19 | 79 ± 15 |
| Cardiac output, l/min | 5.5 ± 0.4 | 4.7 ± 0.3† | 5.2 ± 1.0 | 4.1 ± 0.8 |
| Mean arterial pressure, mmHg | 95 ± 3 | 96 ± 3 | 98 ± 4 | 98 ± 5 |
Values are means ± SE.
†
P < 0.05, significant difference between control and NG-monomethyl-l-arginine (l-NMMA).