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Hemorrhage frequency is not altered by treatment, age, or genotype. Scatter plots show the numbers of young and aging WT and Nrf2−/− mice that displayed intraparenchymal bleeding following administration of vehicle or EC. Despite a trend toward increased hemorrhage for Nrf2−/− mice, analyses revealed no significant differences in intraparenchymal bleeding across treatment, age, or genotype (P = 0.59). E15, 15 mg/kg EC.
