Figure 1. Development patterns of objective response and local recurrence according to the follow-up duration in hepatocellular carcinoma (HCC) patients treated with radiotherapy.

A, the objective response rate increased over time during follow-up. B, the local recurrence rate increased over time during follow-up. C, development pattern of objective response according to age. Older patients showed delayed objective responses. D, development pattern of objective response according to α-fetoprotein (AFP) concentration change. The patients whose post-treatment AFP concentrations were higher than their pre-treatment AFP concentrations (AFP concentration change ≥ 1) showed delayed objective responses.