Table 3. HPLC Analyses of the Enzymatic Assays of l-Tryptophan and Derivatives with rhIDO (Retention Times and MS).
Retention times determined by HPLC analyses (or UPLC analyses; see Supporting Information). Elution conditions: CH3CN/ammonium acetate (10 mM), 10/90 (v/v), flow 0.7 mL/min.
UV detection (method A) at 221 and 284 nm.
UV detection (method A) at 321 or 360 nm.
Mass spectra (see Supporting Information).
Retention times determined by HPLC analyses (or UPLC analyses; see Supporting Information). Elution conditions: CH3CN/ammonium acetate (10 mM), 5/95 (v/v), flow 0.7 mL/min.
Racemate. n.o.: not observed because hydrolysis of the formyl substituent was too fast in these conditions.