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. 2015 Mar 15;21:293–305.

Table 5. Cytokine concentrations (Log pg/ml) in tears that were consistent between subject groups.

Cytokine Stage Group 1
Group 2
Morning
Evening
Combined
Morning
Evening
Combined
Mean SD Mean SD Mean SD Mean SD Mean SD Mean SD
G-CSF
No contact lens
3.6
0.8
3.7
0.8
3.7
0.8
3.2
1.0
3.2
1.1
3.2
1.1
With contact lens wear
3.5
0.9
3.5
0.8
3.5
0.8
3.3
0.7
2.8
1.2
3.1
1.1
Both stages
3.5
0.8
3.6
0.8
3.6
0.8
3.3
0.9
3.0
1.2
3.2
1.1
IL-12p70
No contact lens
5.0
0.7
5.2
0.6
5.1
0.7
4.7
1.0
5.0
0.7
4.9
0.9
With contact lens wear
4.9
0.7
4.9
0.9
4.9
0.8
4.8
0.6
4.6
0.7
4.7
0.7
Both stages
4.9
0.7
5.1
0.8
5.0
0.8
4.8
0.8
4.8
0.7
4.8
0.8
IL-13
No contact lens
3.8
0.7
4.1
0.6
4.0
0.7
3.3
1.5
3.9
1.0
3.6
1.3
contact lens Wear
3.7
0.7
3.9
0.9
3.8
0.8
3.4
1.3
3.2
1.2
3.3
1.2
Both stages
3.8
0.7
4.0
0.8
3.9
0.7
3.4
1.3
3.6
1.2
3.5
1.3
IL-15
No contact lens
2.2
1.1
2.3
1.2
2.2
1.1
1.2
2.3
1.7
3.1
1.5
2.7
With contact lens wear
1.8
1.2
2.1
1.1
2.0
1.2
1.1
2.2
1.0
1.9
1.0
2.0
Both stages
2.0
1.2
2.2
1.1
2.1
1.2
1.2
2.2
1.3
2.6
1.2
2.4
IL-1β
No contact lens
3.4
0.5
3.3
0.6
3.4
0.5
3.1
1.4
3.0
1.7
3.0
1.5
With contact lens wear
3.2
0.6
3.1
0.9
3.1
0.7
2.8
1.2
2.4
1.3
2.6
1.3
Both stages
3.3
0.5
3.2
0.7
3.2
0.6
3.0
1.3
2.7
1.5
2.8
1.4
IL-1Ra
No contact lens
8.0
0.6
8.0
0.7
8.0
0.7
8.1
1.2
7.8
1.0
7.9
1.1
With contact lens wear
7.9
0.7
7.9
0.7
7.9
0.7
7.7
0.9
7.7
1.3
7.7
1.1
Both stages
8.0
0.7
7.9
0.7
7.9
0.7
7.9
1.1
7.7
1.1
7.8
1.1
IL-4
No contact lens
3.7
0.8
3.9
0.7
3.8
0.8
3.2
1.3
3.6
1.1
3.4
1.2
With contact lens wear
3.5
0.9
3.7
1.0
3.6
0.9
3.2
1.3
3.0
1.4
3.1
1.4
Both stages
3.6
0.9
3.8
0.9
3.7
0.9
3.2
1.3
3.3
1.3
3.3
1.3
IL-5
No contact lens
3.8
1.0
4.1
0.8
4.0
0.9
3.5
1.2
4.0
1.1
3.8
1.2
With contact lens wear
3.7
0.9
3.9
0.8
3.8
0.9
3.4
1.3
3.3
1.3
3.3
1.3
Both stages
3.8
0.9
4.0
0.8
3.9
0.9
3.4
1.2
3.6
1.3
3.5
1.3
IL-6
No contact lens
4.1
0.7
4.4
0.6
4.3
0.7
4.0
1.2
3.8
1.4
3.9
1.3
With contact lens wear
3.9
0.8
4.0
0.9
4.0
0.8
4.1
0.9
3.6
1.3
3.8
1.1
Both stages
4.0
0.8
4.2
0.8
4.1
0.8
4.0
1.1
3.7
1.4
3.9
1.2
IL-7
No contact lens
7.0
0.4
7.1
0.4
7.1
0.4
7.2
0.5
7.1
0.5
7.2
0.5
With contact lens wear
6.8
0.5
6.7
1.4
6.8
1.0
7.1
0.4
7.1
0.5
7.1
0.5
Both stages
6.9
0.4
6.9
1.0
6.9
0.8
7.1
0.5
7.1
0.5
7.1
0.5
IL-8
No contact lens
6.5
0.8
5.9
0.5
6.2
0.7
6.4
1.5
5.3
0.8
5.9
1.3
With contact lens wear
6.2
0.9
5.9
0.6
6.0
0.8
6.0
1.1
5.4
1.2
5.7
1.1
Both stages
6.3
0.8
5.9
0.6
6.1
0.8
6.2
1.3
5.3
1.0
5.8
1.2
MIP-1α
No contact lens
4.1
0.9
3.9
1.0
4.0
1.0
4.3
2.5
4.0
2.2
4.1
2.3
With contact lens wear
3.9
1.0
3.8
1.2
3.8
1.1
4.0
2.1
3.0
1.7
3.5
2.0
Both stages
4.0
1.0
3.8
1.1
3.9
1.0
4.1
2.3
3.5
2.0
3.8
2.2
TNF-α
No contact lens
4.4
2.3
5.1
1.5
4.8
2.0
4.0
2.2
4.7
2.0
4.4
2.1
With contact lens wear
4.1
2.3
4.6
2.1
4.3
2.2
4.6
1.6
4.1
2.1
4.3
1.9
Both stages
4.2
2.3
4.8
1.8
4.5
2.1
4.3
2.0
4.4
2.0
4.3
2.0
VEGF No contact lens
5.3
1.0
5.1
1.0
5.2
1.0
4.8
1.9
3.8
2.5
4.3
2.3
With contact lens wear
4.9
1.1
5.0
0.8
5.0
1.0
5.2
1.7
4.9
1.9
5.1
1.8
Both stages 5.1 1.1 5.1 0.9 5.1 1.0 5.0 1.8 4.4 2.3 4.7 2.1

Abbreviations: IL = interleukin; FGF = fibroblast growth factor; G-CSF = Granulocyte colony stimulating factor; GM-CSF = granulocyte monocyte colony stimulating facotr; IFN = interferon; IP = Interferon gamma-induced protein; MCP = monocyte chemoattractant protein; MIP = macrophage inflammatory protein; PDGF = platelet-derived growth factor; RANTES = regulated on activation, normal T cell expressed and secreted; TNF = tumor necrosis factor; VEGF = vascular endothelial growth factor