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. 2015 Mar 15;142(6):1137–1145. doi: 10.1242/dev.116632

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© 2015. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 5. — Normal macular development is required for normal expression of otog and tecta. (A) otog mRNA expression at the poles of the OV of a 21 hpf wild-type (LWT strain) OV. (B) Expression of otog was reduced in the OV of atoh1b morphants. (C) Expression of tecta at the poles of a 21 hpf wild-type OV. (D) tecta expression was not detected in the OV of atoh1b morphants. (E) otog expression in the utricular macula of a 31 hpf phenotypically wild-type sibling embryo. (F) otog expression was reduced in the utricular macula of a 31 hpf mib mutant embryo. (G) tecta expression in the utricular macula of a 31 hpf phenotypically wild-type sibling embryo. (H) tecta expression was reduced in the utricular macula of a 31 hpf mib mutant embryo. Weak expression remained in the saccular macula (out of focus). Dorsal (A-D) and lateral (E-H) views, with anterior to left. Scale bar: 50 µm for A-H.