Fig 2.

Inhibition of complement-mediated haemolysis by C5 inhibitors. The upper panel shows a titration of Ornithodoros moubata complement inhibitor (OmCI) (a) or eculizumab (b) for blocking of haemolysis mediated by the classical complement pathway. The bottom panel shows analogous data for the alternative complement pathway (c, OmCI; d, eculizumab). Heat-inactivated normal human serum (Δ NHS) was used as a negative control. Data were collected from three independent experiments and error bars show standard deviation.