Table 7.
Amino acid sequences of human leucocyte antigen (HLA)-E that are E-restricted and those shared by one or more HLA-Ia and Ib alleles (extracted and modified from references 14,16,70)
| Peptide sequences of two HLA-E alleles | Number of HLA alleles | ||||||
|---|---|---|---|---|---|---|---|
| Classical class Ia | Non-classical class Ib | ||||||
| HLA-E107G & HLA-E107R | No. of amino acids | A | B | Cw | F | G | Specificity |
| 65RSARDTA71 | 7 | 0 | 0 | 0 | 0 | 0 | E-restricted |
| 90AGSHTLQW97 | 8 | 1 | 10 | 48 | 0 | 0 | Polyspecific |
| 102ELGPDR(G)RF109 | 8 | 0 | 0 | 0 | 0 | 0 | E-restricted |
| 115QFAYDGKDY123 | 9 | 1 | 104 | 75 | 0 | 0 | Polyspecific |
| 117AYDGKDY123 | 7 | 491 | 831 | 271 | 21 | 30 | Polyspecific |
| 126LNEDLRSWTA135 | 10 | 239 | 219 | 261 | 21 | 30 | Polyspecific |
| 137DTAAQI142 | 6 | 0 | 824 | 248 | 0 | 30 | Polyspecific |
| 137DTAAQIS143 | 7 | 0 | 52 | 4 | 0 | 30 | Polyspecific |
| 143SEQKSNDASE152 | 10 | 0 | 0 | 0 | 0 | 0 | E-restricted |
| 163TCVEWL168 | 6 | 282 | 206 | 200 | 0 | 30 | Polyspecific |
Position 107 may have either [R] or [G]; only peptides with six or more amino acids are shown in the Table.