Figure 6.

Effect of increasing the tone of endocannabinoids (eCBs) on the field excitatory postsynaptic potentials/population spike (fEPSP/PS). Time course (a, b, d, e) and average magnitude (c, f) of the effect of the eCB uptake inhibitor LY 2183240 (5-[(1,1’-Biphenyl]-4-yl)methyl]-N,N-dimethyl-1H-tetrazole-1-carboxamide) (0.5–1 µM) on the amplitude of the fEPSP/PS measured in the nucleus accumbens (NAc) (a-c) and DLS (b-f). n=5 to 9 slices in each condition. Insets show records of fEPSP/PSs measured in 4 slices at the time points indicated on the graphs.