Table 1.
Seed | Direction | Region | MNI Coordinates | Voxels | Z-Score | ||
---|---|---|---|---|---|---|---|
X | Y | Z | |||||
Left BL | PBO > THC | R cerebelum | 38 | −42 | −32 | 82 | 3.02 |
Left BL | THC > PBO | R Rostral anterior cingulate/mPFC | 14 | 42 | 12 | 398 | 3.65 |
L superior frontal gyrus | −18 | 56 | 4 | 104 | 3.59 | ||
Right BL | PBO > THC | R parietal lobe | 30 | −52 | 70 | 111 | 2.95 |
Right BL | THC > PBO | Middle cingulate gyrus | −2 | 26 | −10 | 55 | 3.31 |
L inferior frontal lobe | −46 | 16 | 18 | 84 | 3.15 | ||
Left CM | PBO > THC | R rectus | 8 | 32 | −26 | 114 | 3.55 |
Left CM | THC > PBO | L inferior frontal lobe | −42 | 22 | 24 | 180 | 3.21 |
Right CM | PBO > THC | L precentral gyrus | −50 | −14 | 58 | 91 | 3.63 |
R parietal lobe | 20 | −56 | 78 | 66 | 3.01 | ||
Right CM | THC > PBO | None | |||||
Left SF | PBO > THC | R precentral gyrus | 60 | 10 | 46 | 117 | 5.19 |
L lingual gyrus | −8 | −96 | −12 | 131 | 4.17 | ||
R superior frontal gyrus | 30 | 58 | 30 | 57 | 2.87 | ||
Left SF | THC > PBO | R posterior frontal lobe | 28 | −38 | 36 | 456 | 3.90 |
R rostral anterior cingulate/mPFC | 14 | 52 | 6 | 760 | 3.71 | ||
Middle cingulate gyrus | 0 | −44 | 42 | 121 | 3.23 | ||
L cingulate gyrus | −16 | −28 | 30 | 67 | 3.10 | ||
L middle frontal lobe | −20 | 18 | 46 | 212 | 3.08 | ||
Right SF | PBO > THC | R superior frontal gyrus | 20 | 48 | 22 | 144 | 3.60 |
R middle temporal gyrus | 54 | −56 | −12 | 312 | 3.32 | ||
L cerebelum | −48 | −54 | −28 | 63 | 3.31 | ||
L fusiform gyrus | −26 | −94 | −24 | 74 | 3.28 | ||
R angular gyrus | 40 | −58 | 30 | 164 | 3.23 | ||
L middle frontal gyrus | −34 | 58 | 14 | 186 | 3.19 | ||
L inferior parietal lobe | −42 | −64 | 46 | 74 | 2.87 | ||
Right SF | THC > PBO | None |
Reporting of all clusters exhibiting significance threshold at P<.005(uncorrected) with a cluster extent threshold of k (number of contiguous voxels) >50. *Bold italics represent a priori areas of interest for significant, corrected for multiple comparisons. gPPI, generalized form of context-dependent psychophysiological interaction analyses; L, left; MNI,Montreal Neurologic Institute; mPFC, medial prefrontal cortex; PBO, placebo; R,right; SF, superficial; THC, Δ9-tetrahydrocannabinol.