Figure 7.

Select examples of compounds containing thiol-reactive chemotypes that demonstrate promiscuous PubChem bioassay profiles. Shown are conspicuous examples of compounds containing chemotypes 1, 2, 3, 4, and 6 that have promiscuous bioassay profiles according to a PubChem substructure search (accessed 1 March 2014). Accompanying each structure is the PubChem CID followed by the ratio (number of bioassays where the compound was classified as active/number of bioassays that the compound was tested).