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Protein kinase C-catalyzed phosphorylation of SIYRRGSRRWRKL peptide (with phosphorylated serine underlined) using ferrocene-labeled ATP (ATP-Fc) as a substrate. After a transfer of γ-phosphate-Fc group to the serine residue of the peptide, the surface-attached Fc groups are detected via EC techniques at thiol-modified gold electrodes. Adapted with permission from ref (754). Copyright 2008 Royal Society of Chemistry.
