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. 2015 Feb 9;115(5):2045–2108. doi: 10.1021/cr500279h

Table 1. Specificity, Source, and Other Properties of the Most Commonly Used Lectinsa.

lectin specificity source source type Mw (kDa) pI SUc glycoprotein metal ions
AAL α-l-Fuc Aleuria aurantia F 72 9 2    
Con A α-d-Man, α-d-Glc Canavalia ensiformis P 104 6.3–7 4   Ca2+, Mn2+
MAA-I Gal-β-(1–4)- GlcNAc Maackia amurensis P 130 4.7 2 yes  
MAA-II Neu5Ac-α-(2–3)β-Gal Maackia amurensis P 130 4.7 2 yes  
PHA-L branched β-(1–6)GlcNAc Phaseolus vulgaris P 126 4.2–4.8 4 yes Ca2+, Mn2+
PHA-E oligo Man Phaseolus vulgaris P 126 6–8 4 yes Ca2+, Mn2+
SNA-Ib Neu5Ac-α-(2–6)Gal Sambucus nigra P 140 5.4–5.8 4 yes  
SNA-II* Gal, GalNAc Sambucus nigra P
RCA-I/RCA120 β-d-Gal Ricinus communis P 120 7.8 2 yes  
RCA-II/RCA60 Gal-β-(1–4)- GalNAc Ricinus communis P 60 7.1 1 yes  
UEA-I α-l-Fuc Ulex europaeus P 63 4.5–5.1 2 yes Ca2+, Mn2+, Zn2+
WGA β-d-GlcNAc Triticum vulgaris P 36 >9 2 no Ca2+
a

Table based on ref (888).

b

SNA (EBL-elderberry bark lectin) is often available only as SNA without any specification, despite the different binding abilities of the two isolectins.

c

F, fungi; P, plant; SU, subunits; Gal, galactose; GalNAc, N-acetylgalactosamine; Glc, glucose; GlcNAc, N-acetylglucosamine; Fuc, fucose; Man, mannose; Neu5Ac, N-acetylneuraminic acid.