Scheme 3. Synthesis of 5-Aminomethylindolyl-pyridinyl-propenones 2h and 2i.
Reagents and conditions: (a) di-tert-butyl dicarbonate, CH3CN, rt; (b) 1. POCl3, DMF; 2. 1 N NaOH; (c) 4-acetylpyridine, piperidine, MeOH, reflux; (d) TFA, MeOH, reflux.
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