Table 1.
N-terminal fragment of the prohormone brain natriuretic peptide level and lipid metabolism parameters after 3-mo of omega-3 polyunsaturated fatty acid therapy
| Parameter |
Patients with T2DM and CAN (n = 36) |
|
| Control (n = 15) | ω-3 PUFA (n = 21) | |
| Group 1 | Group 2 | |
| NT-proBNP | -3.0 ± 1.1 | -6.8 ± 1.1a |
| LDL cholesterol | -8.3 ± 1.4 | -12.8 ± 1.9 |
| HDL cholesterol | 4.1 ± 1.0 | 7.1 ± 0.5a |
| ТG | -8.3 ± 1.2 | -35.4 ± 2.6c |
| TC | -6.7 ± 1.0 | -8.2 ± 1.1 |
The results are presented as % change from baseline, (Δ%, Mean ± SEM);
a
P < 0.05,
c
P < 0.001. T2DM: Type 2 diabetes mellitus; CAN: Cardiac autonomic neuropathy; ω-3 PUFA: Omega-3 polyunsaturated fatty acid; NT-proBNP: N-terminal fragment of the prohormone brain natriuretic peptide; LDL cholesterol: Low density lipoprotein cholesterol; HDL cholesterol: High density lipoprotein cholesterol; ТG: Triglycerides; TC: Total cholesterol.