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. 2015 Mar 15;6(2):358–366. doi: 10.4239/wjd.v6.i2.358

Table 2.

Risk allele frequencies for the tested gene variants among Omani type 2 diabetes mellitus patients and control participants

Gene Gene variant Risk/non- Risk allele frequency (f)
1P value OR 95%CI
(SNPs) risk allele T2D patients (n = 992) Controls (n = 294) for OR
KCNJ11 rs5219 T/C 0.320 0.222 25.8 × 10-6 1.74 1.37-2.22
TCF7L2 rs7903146 T/C 0.445 0.354 20.001 1.46 1.16-1.83
CDKAL1 rs10946398 C/A 0.364 0.311 20.002 1.44 1.15-1.80
CDKN2A/B rs10811661 T/C 0.836 0.799 0.020 1.40 1.06-1.84
FTO rs9939609 A/T 0.480 0.435 0.358 1.11 0.899-1.37
FTO rs8050136 A/C 0.458 0.425 0.770 1.03 0.829-1.29
IGF2BP2 rs4402960 T/G 0.400 0.357 0.286 1.13 0.904-1.41
SLC30A8 rs13266634 C/T 0.857 0.855 0.329 1.16 0.859-1.57
CAPN10 rs3792267 (-43) G/A 0.802 0.790 0.445 1.11 0.850-1.45
HHEX rs1111875 T/C 0.301 0.280 0.636 1.06 0.839-1.33

1P value: Level of significance;

2

P value remained significant after correction for multiple testing (< 0.005). The P value, OR and 95%CI were calculated for the association between each gene variant with T2D risk. f: Frequency; T2D: Type 2 diabetes mellitus; SNPs: Single nucleotide polymorphisms.