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. 2015 Mar 15;6(2):358–366. doi: 10.4239/wjd.v6.i2.358

Table 3.

Fixation index, heterozygosity, Fst and % variation among Omani type 2 diabetes mellitus patients and control participants

Gene Gene variants T2D patients
Controls
Fst % variation among T2D and controls 1P value
F He F He
KCNJ11 rs5219 0.190 0.352 0.091 0.314 0.012 2.07 0.000
TCF7L2 rs7903146 0.017 0.486 0.000 0.476 0.009 1.62 0.000
CDKAL1 rs10946398 0.084 0.424 0.056 0.405 0.003 0.48 0.020
CDKN2A/B rs10811661 0.000 0.275 0.003 0.320 0.002 0.37 0.042
FTO rs9939609 0.000 0.502 0.000 0.497 0.002 0.31 0.050
FTO rs8050136 0.006 0.493 0.000 0.503 0.001 0.12 0.147
IGF2BP2 rs4402960 0.066 0.448 0.000 0.476 0.002 0.23 0.089
SLC30A8 rs13266634 0.061 0.230 0.188 0.201 0.000 0.00 1.000
CAPN10 rs3792267 0.057 0.300 0.000 0.335 0.000 0.00 0.517
HHEX rs1111875 0.055 0.398 0.052 0.382 0.001 0.00 0.341

This provides a measure of genetic differentiation among population; 1P value: Level of significance; F: Fixation index; He: Heterozygosity; Fst: The inbreeding coefficient within subpopulation, relative to total; T2D: Type 2 diabetes mellitus.