Table 1.
Summary of 60 collagenous gastritis patients
| Ref. | Age (yr) | Gender |
Symptoms |
Endoscopic Findings |
H. pylori |
Collagen band (μm) |
Treatment | Follow-up biopsy duration (yr) | Histological changes | Clinical course | ||||||||
| Abdominal pain | Anemia | Diarrhea | Nausea, vomiting | Others | Nodularity | Erythema | Erosion, gastritis | Others | Stomach | Colon | ||||||||
| [10] | 7 | F | + | + | - | - | - | - | - | + | - | NA | Yes | None | Oral iron supplementation, Proton-pump inhibitor | 0.5 | Improvement of inflammation remaining of collagen band | Improve |
| [11] | 9 | F | - | + | - | - | Retrosternal pain | - | + | - | - | - | 13-96 | < 5 | Proton-pump inhibitor, Sucralfate, Steroid | 1.1 | No reduction | No change |
| [12] | 9 | F | + | - | - | - | - | - | - | + | - | - | 35 | None | Oral iron supplementation | 4 | Decrease of chronic gastritis, Unchanged collagen bands | Clinical remission |
| [13] | 9 | F | + | - | - | - | - | + | - | - | - | - | Yes | Yes | Oral iron supplementation | NA | NA | Improve |
| [14] | 9 | F | + | + | - | - | - | - | - | - | NA | NA | Yes | NA | Mesalazine | NA | Remain | |
| [15] | 12 | F | - | - | - | + | - | + | - | - | - | + | NA | None | Proton-pump inhibitor | 1 | Severe erosive gastritis | Remain |
| [15] | 12 | F | + | - | - | - | - | + | - | - | - | + | NA | None | Proton-pump inhibitor | 6 | Decrease of nodules | Improve |
| [15] | 12 | F | + | - | - | - | - | + | - | - | - | + | NA | NA | Proton-pump inhibitor | 0.17 | NA | Improve |
| [16] | 12 | F | - | + | - | - | - | + | - | - | - | - | Yes | None | Oral iron supplementation | NA | ||
| [17] | 13 | F | - | + | - | - | - | + | - | - | - | - | 76 | NA | None | NA | NA | NA |
| [18] | 14 | F | + | - | - | - | - | + | - | - | - | - | 75 | None | Proton-pump inhibitor, Sucralfate, H2-receptor antagonist | 12 | Gradual progression | Remain |
| [17] | 14 | F | - | - | - | + | - | - | - | + | - | - | 23 | NA | Proton-pump inhibitor | NA | NA | Remain |
| [8] | 15 | F | + | + | - | - | Gastrointestinal bleeding | + | - | - | - | - | 75 | None | H2-receptor antagonist, sucralfate, furazolidone | 2 | No reduction | NA |
| [19] | 15 | F | - | + | - | - | - | + | - | - | - | + | NA | NA | Proton-pump inhibitors, Oral iron supplementation, Steroid | 0.83 | NA | Clinical remission |
| [17] | 15 | F | + | + | - | - | - | + | - | - | - | - | 69 | None | Steroid | 3.4 | Decrease of inflammation | Improve |
| [4] | 16 | F | + | + | - | - | - | + | - | - | - | - | NA | None | H2-receptor antagonist, Proton-pump inhibitor, Oral iron supplementation, | 6 | No reduction | Improvement of anemia |
| [20] | 20 | F | + | - | - | - | - | + | - | - | - | - | 30-70 | None | Proton-pump inhibitor | 2 | No change | NA |
| [21] | 22 | F | - | + | - | - | - | + | - | - | - | - | 40-45 | NA | None | NA | NA | NA |
| [40] | 22 | F | + | + | - | - | Gastrointestinal bleeding | + | - | + | Duodenitis | - | 60-100 | None | H2-receptor antagonist,Proton-pump inhibitor | 1 | No change | Improve |
| [22] | 25 | F | - | + | - | - | - | + | - | - | - | - | 24 | Yes | None | 0.25 | No change | NA |
| [23] | 25 | F | - | - | + | - | - | - | - | - | NA | NA | Yes | NA | None | NA | NA | NA |
| [23] | 25 | F | - | - | + | - | Body weight loss | - | - | - | NA | NA | Yes | Yes | NA | NA | NA | NA |
| [39] | 25 | F | + | + | - | - | - | + | - | - | NA | - | 17 | None | H2-receptor antagonist,Proton-pump inhibitor | 4 | No change | No change |
| [24] | 35 | F | - | - | + | - | Abdominal distention | + | - | - | - | - | 20-30 | None | Sulfasalazine | NA | NA | Remission of diarrhea |
| [4] | 39 | F | - | + | - | - | Fatigue | - | - | - | Normal | - | NA | Yes | Gluten-free diet | 4 | No reduction | Improve |
| [21] | 40 | F | - | - | + | - | - | - | - | - | Normal | - | 40-41 | None | Steroid, Sulfasalazine, Parenteral nutrition | 2 | Resolve of collagen band | NA |
| [21] | 52 | F | - | + | - | - | - | - | - | - | Normal | + | 15-20 | None | None | NA | NA | NA |
| [17] | 52 | F | + | - | + | - | - | - | - | + | - | - | 78 | None | Gluten-free diet | NA | NA | Improve |
| [25] | 57 | F | - | - | + | - | - | - | + | - | - | - | 20-40 | > 30 | Steroid | 1.5 | No change | Responded to steroid |
| [17] | 57 | F | + | - | - | - | - | + | - | - | - | - | 40 | NA | Gluten-free diet | NA | NA | Improve |
| [22] | 58 | F | - | - | + | - | - | + | - | - | - | - | 15.8 | None | Steroid | 1.5 | Improvement of inflammation remaining of collagen band | NA |
| [17] | 62 | F | - | - | - | + | - | - | - | + | - | - | 94 | NA | None | NA | NA | NA |
| [2] | 68 | F | - | + | - | - | Dyspepsia | + | - | - | - | - | None | None | Oral iron supplementation, Proton-pump inhibitor | 0.83 | Improvement of inflammation increase of collagen band | Partial relief |
| [26] | 74 | F | + | - | + | - | - | - | + | - | - | - | Yes | Yes | Proton-pump inhibitor | 0.08 | No change | Improve |
| [27] | 75 | F | - | - | + | - | - | - | - | - | Normal | NA | 30-60 | 10-30 | NA | NA | NA | NA |
| [28] | 0.75 | M | - | - | + | - | - | - | - | + | - | + | 50 | 17 | Steroid, Total parenteral nutrition | 14 | Gradual progression | Improve with total parenteral nutrition |
| [29] | 2 | M | - | - | + | - | - | - | - | + | - | + | > 5 | NA | Proton-pump inhibitors, Mesalazine, Steroid, Bismuth subsalicylate | NA | NA | Improve |
| [30] | 9 | M | + | + | - | - | - | + | - | - | - | - | 30-150 | None | Oral iron supplementation | 2 | NA | NA |
| [21] | 11 | M | - | + | - | - | - | + | - | - | - | - | 50-69 | None | None | 8 | Moderate decrease | NA |
| [10] | 11 | M | + | + | - | - | - | + | - | - | - | NA | > 10 | NA | Proton-pump inhibitor, Oral iron supplementation | 5 | Improvement of inflammationresolve of collagen band | Improve |
| [13] | 15 | M | - | - | + | - | - | + | - | - | - | - | 30 | 30 | Proton-pump inhibitor, Steroid, Mesalazine | NA | NA | Clinical remission |
| [17] | 19 | M | + | + | - | - | Perforation of ulcer | + | - | - | - | - | 40 | NA | Sucralfate | 0.25 | Improvement of inflammationdecrease of collagen band | Improve |
| [38] | 19 | M | + | - | - | - | Constipation | + | - | - | - | NA | 15 | None | None | 0.5 | Progression | Improve |
| [31] | 20 | M | + | - | - | + | - | + | - | - | - | - | 15-43 | 20-30 | H2-receptor antagonist, Oral iron supplementation | 4 | Progression | No change |
| [32] | 25 | M | + | - | - | + | Abdominal distention | + | - | - | - | - | > 10 | None | Proton-pump inhibitor | NA | NA | Improve |
| [33] | 25 | M | + | - | - | - | - | - | - | - | Normal | + | Yes | NA | None | NA | NA | NA |
| [17] | 34 | M | + | + | - | - | Gastrointestinal bleeding | + | - | - | - | - | 78 | NA | None | 9.9 | Gradual progression | NA |
| [33] | 35 | M | - | - | - | - | - | + | - | - | - | - | 50 | None | None | 14 | Increase | Increase |
| [21] | 36 | M | NA | NA | NA | NA | NA | - | - | - | NA | - | 15-20 | NA | None | NA | NA | NA |
| [35] | 37 | M | - | - | + | - | Body weight loss | + | - | - | - | - | 120 | None | Steroid, Azathioprine, Parenteral nutrition | 1.67 | No change | Improve |
| [36] | 42 | M | - | + | + | - | Abdominal distention, Rectal bleeding | - | + | - | - | NA | 26-10 | None | Gluten-free diet | 0.25 | No change | Improve |
| [9] | 47 | M | + | - | - | - | - | - | - | - | Normal | + | 70 | None | Proton-pump inhibitor | NA | NA | Improve |
| [17] | 56 | M | - | - | - | + | - | + | - | - | - | - | 87 | None | Steroid, Gluten-free diet | NA | NA | Improve |
| [3] | 56 | M | + | - | - | + | Body weight loss | - | - | + | - | NA | Yes | NA | NA | NA | NA | NA |
| [37] | 57 | M | - | + | + | - | - | - | + | - | - | NA | 13-45 | None | Steroid, Mesalazine | NA | NA | Improve |
| [17] | 59 | M | - | - | - | - | Dysphagia | - | - | - | Normal | - | 54 | NA | None | NA | NA | NA |
| [17] | 68 | M | - | - | + | - | - | - | - | + | - | - | 20 | NA | Steroid, Gluten-free diet | 0.75 | Gradual progression | Remain |
| [23] | 72 | M | - | - | + | - | Body weight loss | - | - | - | NA | NA | Yes | Yes | Steroid | NA | NA | Improve |
| [21] | 77 | M | - | - | - | - | - | - | - | + | - | + | 20-28 | NA | None | NA | NA | NA |
| [17] | 80 | M | - | + | + | - | - | + | - | - | - | - | 47 | None | Steroid | NA | NA | NA |
NA: Not available.