Table 2.

Predictors of response to antiviral treatment in patients with hepatitis C virus genotype 4 infection

Predictor	Ref.
Age	[57]
Liver histopathology (advanced fibrosis/severe steatosis)	[40,52,54,60]
Baseline viral load1	[42,43]
Ethnicity	[52,54]
Diabetes/Insulin resistance	[49,54,57]
IL28B polymorphisms	[58,63]
Plasma levels of IP-102	[59]
HCV 4 subtypes	[52]
Co-infections (HIV, Schistosomiasis)	[38,61]

¹Most studies used a cut-off value of 400.000 IU/mL;

²Interferon-c inducible protein 10. HCV: Hepatitis C virus; HIV: Human immunodeficiency virus; IP-10: Inducible protein 10.