Table 1.
EVcomplex predictions and docking results for 15 protein complexes
| EVcomplex contacts | Docking quality (iRMSD) | |||||
|---|---|---|---|---|---|---|
| Complex name | Subunits | Seqs† | ECs‡ | TP rate§ | Top ranked model# | Best model¶ |
| Carbamoyl-phosphate synthase | CarB:CarA | 2.3 | 17 | 0.88 | 1.9 | 1.9 |
| Aminomethyltransferase/Glycine cleavage system H protein | GcsH:GcsT | 2.9 | 5 | 0.2 | 5.4 | 5.4 |
| Histidine kinase/response regulator | KdpD:CheY (T. maritima) | 95.4 | 78 | 0.72 | 2.1 | 2.0 |
| Ubiquinol oxidase | CyoB:CyoA | 1.0 | 11 | 0.55 | 1.8 | 1.2 |
| Outer membrane usher protein/Chaperone protein | FimD:FimC | 3.6 | 6 | 0.83 | 3.2 | 3.0 |
| Molybdopterin synthase | MoaD:MoaE | 3.6 | 8 | 1.0 | 4.4 | 4.1 |
| Methionine transporter complex | MetN:MetI | 1.9 | 14 | 0.86 | 1.5 | 1.2 |
| Dihydroxyacetone kinase | DhaL:DhaK | 1.4 | 12 | 0.42 | 6.7 | 2.4 |
| Vitamin B12 uptake system | BtuC:BtuF | 3.2 | 5 | 0.6 | 2.8 | 2.8 |
| Vitamin B12 uptake system | BtuC:BtuD | 9.8 | 21 | 0.88 | 1.1 | 0.9 |
| ATP synthase γ and ε subunits | AtpE:AtpG | 2.9 | 15 | 0.53 | 1.4 | 1.4 |
| IIA-IIB complex of the N,N'-diacetylchitobiose (Chb) transporter | PtqA:PtqB | 3.1 | 5 | 0.2 | 7.2 | 5.5 |
| 30 S Ribosomal proteins | RS3:RS14 | 1.4 | 11 | 0.91 | 1.1 | 1.1 |
| Succinatequinone oxido-reductase flavoprotein/iron-sulfur subunits | SdhB:SdhA | 3.0 | 8 | 0.62 | 1.4 | 1.4 |
| 30 S Ribosomal proteins | RS10:RS14 | 1.2 | 6 | 1.0 | 5.3 | 2.5 |
†
Number of non-redundant sequences in concatenated alignment normalized by alignment length.
‡
Inter-ECs with EVcomplex score ≥0.8.
§
True Positive rate for inter-ECs above score threshold.
#
iRMSD positional deviation of model from known structure, for docked model with best HADDOCK score.
¶
Lowest iRMSD observed across all models.