Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	206 women 3 RCTs in this analysis	Withdrawal owing to serious adverse effects (not further defined) with fluconazole with itraconazole Absolute results not reported	OR 0.72 95% CI 0.16 to 3.32		Not significant
Systematic review	809 people 3 RCTs in this analysis	Adverse effects of the nervous system with fluconazole with itraconazole Absolute results not reported	OR 1.07 95% CI 0.42 to 2.73		Not significant
Systematic review	759 women 3 RCTs in this analysis	Adverse effects of the digestive system with fluconazole with itraconazole Absolute results not reported	OR 1.84 95% CI 0.3 to 11.27		Not significant